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Author Topic: Enzymological analysis of the effects of chloroquine on Casein Kinases from...  (Read 1888 times)
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Francis Umeoguaju
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« on: October 16, 2012, 02:52:34 am »


Enzymological analysis  of the effects of  chloroquine on Casein Kinases from wisrat rats liver


Akinribido F.A ,Okanlawon O.A, Yama O.E
Dept  Department of Biological Sciences, Bells University of Technology Ota, Ogun State
Dept Of Anatomy,College of Medicine, University of Lagos, Idi-Araba, Lagos State
(Research Work)
Correspondence to: Akinribido F.A, fumibos@yahoo.co.uk; +2348023654975

ABSTRACT

Ten male rats were exposed to chloroquine phosphate injection intraperitoneally /IP) for three days. The treated rats received 0.125ml/100g body weight of chloroquine phosphate injection intraperitoneally. Control rats received the same amount of normal saline intraperitoneally. Enzyme assay was carried out on the liver and compared with controls. It was observed that chloroquine caused significant reduction in the enzyme activity of the Cyclic-AMP Independent Casein Kinases from rats liver cytosol of the treated rats compared with controls.


Keywords: casein kinases,wisrat rats, chloroquine, enzymological analysis ,liver
« Last Edit: October 16, 2012, 02:54:11 am by Francis Umeoguaju » Logged

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