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Author Topic: Short term effects of chloroquine on the enzyme activity of Cyclic- AMP independ  (Read 1952 times)
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funmilayo
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« on: April 02, 2012, 07:10:13 am »


Short term effects of chloroquine on the enzyme activity of Cyclic- AMP independent casein kinases from Sprague Dawley rats liver cytosol

Akinribido F.A ,Okanlawon O.A, Yama O.E (2012)
Dept  Department of Biological Sciences, Bells University of Technology Ota, Ogun State
Dept Of Anatomy,College of Medicine, University of Lagos, Idi-Araba, Lagos State
(Research Work)
 Correspondence to: Akinribido F.A, fumibos@yahoo.co.uk; +2348023654975


ABSTRACT
For a very short period of three days, ten male rats were exposed to chloroquine phosphate injection intraperitoneally /IP) for three days. The treated rats received 0.125ml/100g body weight of chloroquine phosphate injection intraperitoneally. Control rats received the same amount of normal saline intraperitoneally.
Enzyme assay was carried out on the liver and compared with controls. It was observed that chloroquine caused significant reduction in the enzyme activity of the cyclic -AMP Independent casein kinases from rats liver cytosol of the treated rats compared with controls.

Keywords:chloroquine,casein kinases,sprague Dawley rats, enzyme activity

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Francis Umeoguaju
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« Reply #1 on: October 16, 2012, 02:14:03 am »


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